Gene Symbol | CAPZA3 |
---|---|
Entrez Gene | 93661 |
Alt Symbol | CAPPA3, Gsg3 |
Species | Human |
Gene Type | protein-coding |
Description | capping protein (actin filament) muscle Z-line, alpha 3 |
Other Description | CP-alpha-3|CapZ alpha-3|F-actin capping protein alpha-3 subunit|F-actin-capping protein subunit alpha-3|germ cell-specific protein 3 |
Swissprots | Q96KX2 Q969J0 |
Accessions | CBH19237 EAW96391 Q96KX2 AB053259 BAB61901 AK058174 BAB71703 BC016745 AAH16745 BG772483 JF432140 ADZ15357 NM_033328 NP_201585 |
Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed exclusively in testis and sperm. Highest expression is found in the neck region of ejaculated sperm with lower levels found in the tail and postacrosome region. {ECO:0000269|PubMed:12029070}. |
CapZ-α3 CRISPR/Cas9 KO Plasmid (h) - sc-413982 from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 HDR Plasmid (h) - sc-413982-HDR from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 Double Nickase Plasmid (h) - sc-413982-NIC from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 Double Nickase Plasmid (h2) - sc-413982-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 CRISPR Activation Plasmid (h) - sc-413982-ACT from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 CRISPR Activation Plasmid (h2) - sc-413982-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 Lentiviral Activation Particles (h) - sc-413982-LAC from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 Lentiviral Activation Particles (h2) - sc-413982-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 siRNA (h) - sc-95744 from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 shRNA Plasmid (h) - sc-95744-SH from Santa Cruz Biotechnology
|
||||||||
CapZ-α3 shRNA (h) Lentiviral Particles - sc-95744-V from Santa Cruz Biotechnology
|
||||||||
CAPZA3 RNAi - H00093661-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU057891 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN5359 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5359 from Sigma-Aldrich
|
||||||||
CAPZA3 siRNA (Human) - CRJ4225 from Cohesion Biosciences
|
||||||||
CAPZA3 - MBS8202614 from MyBioSource
|
||||||||
shRNA set against Human CAPZA3 (NM_033328.2) - SHH254521 from Creative biogene
|
||||||||
shRNA set against Human CAPZA3(NM_033328.2) - SHG133651 from Creative biogene
|
||||||||
CAPZA3 shRNA Plasmid (Human) - CHJ4225 from Cohesion Biosciences
|
||||||||
CAPZA3 miRNA 3'UTR clone - MiUTR1H-01668 from Creative biogene
|