CTC1

Gene Symbol CTC1
Entrez Gene 80169
Alt Symbol AAF-132, AAF132, C17orf68, CRMCC, tmp494178
Species Human
Gene Type protein-coding
Description CTS telomere maintenance complex component 1
Other Description CST complex subunit CTC1|HBV DNAPTP1-transactivated protein B|alpha accessory factor 132|conserved telomere capping protein 1
Swissprots Q1PCD1 Q2TBE3 C9JEX5 B3KR66 Q2NKJ3 Q9H6L0 Q8N3S6
Accessions EAW90070 EAW90071 Q2NKJ3 AK025823 BAB15247 AK091077 BAG52278 AK225375 AK310636 AL831955 CAD38600 BC026057 AAH26057 BC110373 AAI10374 BC111783 AAI11784 BF798182 BU631459 BX406692 DA313518 DB126489 DQ451688 ABE02809 FJ790670 ACY71127 HG508640 XM_006721577 XP_006721640 XM_006721578 XP_006721641 XM_006721579 XP_006721642 XM_011524010 XP_011522312 XM_011524011 XP_011522313 XR_429823 XR_429824 XR_429825 NM_025099 NP_079375 NR_046431
Function Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. {ECO:0000269|PubMed:19854130, ECO:0000269|PubMed:19854131}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19854130}. Chromosome, telomere {ECO:0000269|PubMed:19854130}. Note=A transmembrane region is predicted by sequence analysis tools (ESKW, MEMSAT and Phobius); however, given the telomeric localization of the protein, the relevance of the transmembrane region is unsure in vivo.

C17orf68 CRISPR/Cas9 KO Plasmid (h) - sc-404616 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 HDR Plasmid (h) - sc-404616-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 Double Nickase Plasmid (h) - sc-404616-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 Double Nickase Plasmid (h2) - sc-404616-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 CRISPR Activation Plasmid (h) - sc-404616-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 CRISPR Activation Plasmid (h2) - sc-404616-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 Lentiviral Activation Particles (h) - sc-404616-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 Lentiviral Activation Particles (h2) - sc-404616-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf68 siRNA (h) - sc-93645 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C17orf68 shRNA Plasmid (h) - sc-93645-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C17orf68 shRNA (h) Lentiviral Particles - sc-93645-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU089931 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4476 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4476 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08989 from Sigma-Aldrich

Category miRNA

CTC1 siRNA (Human) - CRJ2782 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTC1 - MBS8218263 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CTC1 (NM_025099.5) - SHH271065 from Creative biogene

Category siRNA
Species Reactivities Human

Human CTC1 siRNA - orb273283 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTC1 shRNA Plasmid (Human) - CHJ2782 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CTC1 miRNA 3'UTR clone - MiUTR4H-TG01428 from Creative biogene

Species Reactivities Human
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