Gene Symbol |
NAB2
|
Entrez Gene |
4665
|
Alt Symbol |
MADER
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NGFI-A binding protein 2 (EGR1 binding protein 2)
|
Other Description |
EGR-1-binding protein 2|EGR1 binding protein 2|NGFI-A-binding protein 2|melanoma-associated delayed early response protein
|
Swissprots |
B2RAK3 Q15742 O76006 Q14797
|
Accessions |
AAF72545 CAA09472 EAW96987 EAW96988 EAW96989 Q15742 AK314229 BAG36900 BC007756 BC065931 AAH65931 DA496543 U48361 AAC50589 X70991 CAA50318 XM_005268894 XP_005268951 NM_005967 NP_005958
|
Function |
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}. Note=Isoform 2 is not localized to the nucleus. {ECO:0000250}.
|
Tissue Specificity |
Widely expressed at low levels. Highly expressed in melanoma cell lines.
|