Gene Symbol | NAB2 |
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Entrez Gene | 4665 |
Alt Symbol | MADER |
Species | Human |
Gene Type | protein-coding |
Description | NGFI-A binding protein 2 (EGR1 binding protein 2) |
Other Description | EGR-1-binding protein 2|EGR1 binding protein 2|NGFI-A-binding protein 2|melanoma-associated delayed early response protein |
Swissprots | B2RAK3 Q15742 O76006 Q14797 |
Accessions | AAF72545 CAA09472 EAW96987 EAW96988 EAW96989 Q15742 AK314229 BAG36900 BC007756 BC065931 AAH65931 DA496543 U48361 AAC50589 X70991 CAA50318 XM_005268894 XP_005268951 NM_005967 NP_005958 |
Function | Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Isoform 2 is not localized to the nucleus. {ECO:0000250}. |
Tissue Specificity | Widely expressed at low levels. Highly expressed in melanoma cell lines. |
NAB2 CRISPR/Cas9 KO Plasmid (h) - sc-402117 from Santa Cruz Biotechnology
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NAB2 HDR Plasmid (h) - sc-402117-HDR from Santa Cruz Biotechnology
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NAB2 Double Nickase Plasmid (h) - sc-402117-NIC from Santa Cruz Biotechnology
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NAB2 Double Nickase Plasmid (h2) - sc-402117-NIC-2 from Santa Cruz Biotechnology
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NAB2 CRISPR Activation Plasmid (h) - sc-402117-ACT from Santa Cruz Biotechnology
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NAB2 CRISPR Activation Plasmid (h2) - sc-402117-ACT-2 from Santa Cruz Biotechnology
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NAB2 Lentiviral Activation Particles (h) - sc-402117-LAC from Santa Cruz Biotechnology
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NAB2 Lentiviral Activation Particles (h2) - sc-402117-LAC-2 from Santa Cruz Biotechnology
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NAB2 siRNA (h) - sc-36014 from Santa Cruz Biotechnology
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NAB2 shRNA Plasmid (h) - sc-36014-SH from Santa Cruz Biotechnology
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NAB2 shRNA (h) Lentiviral Particles - sc-36014-V from Santa Cruz Biotechnology
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Nab2 RNAi - H00004665-R01 from Novus Biologicals
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MISSION® esiRNA - EHU122911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14919 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14919 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06591 from Sigma-Aldrich
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NAB2 siRNA (Human) - CRH3083 from Cohesion Biosciences
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shRNA set against Human NAB2 (NM_005967.3) - SHH348900 from Creative biogene
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shRNA set against Human NAB2(NM_005967.3) - SHH214715 from Creative biogene
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Human NAB2 siRNA - orb263585 from Biorbyt
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NAB2 shRNA Plasmid (Human) - CHH3083 from Cohesion Biosciences
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NAB2 miRNA 3'UTR clone - MiUTR1H-06621 from Creative biogene
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