Gene Symbol |
GPR65
|
Entrez Gene |
8477
|
Alt Symbol |
TDAG8, hTDAG8
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
G protein-coupled receptor 65
|
Other Description |
G-protein coupled receptor 65|T-cell death-associated gene 8 protein|psychosine receptor
|
Swissprots |
Q8IYL9 O75819
|
Accessions |
AAC31794 CCF77055 EAW81365 Q8IYL9 AK313797 BAG36533 BC035633 AAH35633 BC071715 AAH71715 DQ890834 ABM81760 DQ893989 ABM84915 EU883574 ACG60648 NM_003608 NP_003599
|
Function |
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation- induced cell death or differentiation of T-cells. {ECO:0000269|PubMed:11309421}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:11309421, ECO:0000269|PubMed:9655242}.
|