Gene Symbol | GPR65 |
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Entrez Gene | 8477 |
Alt Symbol | TDAG8, hTDAG8 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 65 |
Other Description | G-protein coupled receptor 65|T-cell death-associated gene 8 protein|psychosine receptor |
Swissprots | Q8IYL9 O75819 |
Accessions | AAC31794 CCF77055 EAW81365 Q8IYL9 AK313797 BAG36533 BC035633 AAH35633 BC071715 AAH71715 DQ890834 ABM81760 DQ893989 ABM84915 EU883574 ACG60648 NM_003608 NP_003599 |
Function | Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation- induced cell death or differentiation of T-cells. {ECO:0000269|PubMed:11309421}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:11309421, ECO:0000269|PubMed:9655242}. |
TDAG8 CRISPR/Cas9 KO Plasmid (h) - sc-416613 from Santa Cruz Biotechnology
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TDAG8 HDR Plasmid (h) - sc-416613-HDR from Santa Cruz Biotechnology
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TDAG8 Double Nickase Plasmid (h) - sc-416613-NIC from Santa Cruz Biotechnology
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TDAG8 Double Nickase Plasmid (h2) - sc-416613-NIC-2 from Santa Cruz Biotechnology
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TDAG8 CRISPR Activation Plasmid (h) - sc-416613-ACT from Santa Cruz Biotechnology
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TDAG8 CRISPR Activation Plasmid (h2) - sc-416613-ACT-2 from Santa Cruz Biotechnology
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TDAG8 Lentiviral Activation Particles (h) - sc-416613-LAC from Santa Cruz Biotechnology
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TDAG8 Lentiviral Activation Particles (h2) - sc-416613-LAC-2 from Santa Cruz Biotechnology
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TDAG8 siRNA (h) - sc-40198 from Santa Cruz Biotechnology
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TDAG8 shRNA Plasmid (h) - sc-40198-SH from Santa Cruz Biotechnology
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TDAG8 shRNA (h) Lentiviral Particles - sc-40198-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU142871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9613 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9613 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02581 from Sigma-Aldrich
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GPR65 siRNA (Human) - CRH5557 from Cohesion Biosciences
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TDAG8/GPR65 RNAi - H00008477-R02 from Novus Biologicals
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GPR65 - MBS8210953 from MyBioSource
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shRNA set against Human Gpr65 (NM_003608.3) - SHH306986 from Creative biogene
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Human GPR65 siRNA - orb266059 from Biorbyt
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GPR65 shRNA Plasmid (Human) - CHH5557 from Cohesion Biosciences
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GPR65 miRNA 3'UTR clone - MiUTR3H-06962 from Creative biogene
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