Gene Symbol | E2F2 |
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Entrez Gene | 1870 |
Alt Symbol | E2F-2 |
Species | Human |
Gene Type | protein-coding |
Description | E2F transcription factor 2 |
Other Description | transcription factor E2F2 |
Swissprots | Q14209 B2R9W1 Q7Z6H1 |
Accessions | AAM54044 EAW95055 EAW95056 EAW95057 EAW95058 Q14209 AF086395 AK092799 AK313939 BAG36658 BC007609 AAH07609 BC053676 AAH53676 BT019523 AAV38330 L22846 AAA16890 XM_005245748 XP_005245805 XM_005245749 XP_005245806 XM_011540868 XP_011539170 XM_011540869 XP_011539171 XM_011540870 XP_011539172 XM_011540871 XP_011539173 NM_004091 NP_004082 |
Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner. |
Subcellular Location | Nucleus. |
Tissue Specificity | Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples. |
Top Pathways | MicroRNAs in cancer, Cell cycle, HTLV-I infection, Prostate cancer, Glioma |
Human E2F2 full length protein - ab114610 from Abcam
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Human E2F2 protein fragment - ab152350 from Abcam
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E2F2 Antibody Blocking Peptide - LS-E245 from LifeSpan Bioscience
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E2F2 Antibody Blocking Peptide - LS-E11048 from LifeSpan Bioscience
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E2F2 Antibody Blocking Peptide - LS-E13803 from LifeSpan Bioscience
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E2F-2 Recombinant Protein - H00001870-P01 from Novus Biologicals
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Recombinant Human E2F-2 Protein - H00001870-Q01 from Novus Biologicals
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E2F2-Antibody-Center-Blocking-Peptide - BP10481c from Abgent, a WuXi AppTec company
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E2F2 Blocking Peptide - abx062553 from Abbexa
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E2F2 - H00001870-P01-10 from Acris Antibodies
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E2F2 - H00001870-P01-25 from Acris Antibodies
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E2F2 - H00001870-Q01-10 from Acris Antibodies
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E2F2 - H00001870-Q01-25 from Acris Antibodies
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E2F2 control peptide - AP09984CP-N from Acris Antibodies
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E2F2 fusion protein - ag6266 from Proteintech Group
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Recombinant Human E2F2 - E2F2-27376TH from Creative Biomart
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Recombinant E2F Transcription Factor 2 (E2F2) - RPJ182Hu01 from Uscn Life Science Inc.
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E2F2 Blocking Peptide - CBP1359 from Cohesion Biosciences
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E2F-2 (K236) Peptide - BS2057P from Bioworld Technology
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Recombinant E2F Transcription Factor 2 (E2F2) - RPJ182Hu01 from Cloud-clone
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Recombinant Human Transcription factor E2F2(E2F2) - CSB-YP623909HU CSB-EP623909HU CSB-BP623909HU CSB-MP623909HU from Cusabio
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E2F2 Peptide, Human - M34GP04665H from Creative Peptides
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Recombinant E2F Transcription Factor 2 (E2F2) - RPU53689 from Biomatik
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E2F2 Recombinant Protein (OPCD02828) - OPCD02828 from Aviva Systems Biology
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E2F Transcription Factor 2, Recombinant Protein - MBS2033367 from MyBioSource
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