Gene Symbol | GNA13 |
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Entrez Gene | 10672 |
Alt Symbol | G13 |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), alpha 13 |
Other Description | G-protein subunit alpha-13|g alpha-13|guanine nucleotide-binding protein subunit alpha-13 |
Swissprots | Q14344 Q8TD70 F5H1G8 B7Z7R0 B2R977 |
Accessions | EAW88993 EAW88994 EAW88995 EAW88996 Q14344 AB075500 AF493902 AAM12616 AK002117 AK026902 AK301699 BAG63171 AK302400 BAH13696 AK313672 BAG36424 AW298099 BC036756 AAH36756 DC335364 DQ893572 ABM84498 DQ894448 ABM85374 L22075 AAA74235 XM_011524202 XP_011522504 XR_934352 NM_001282425 NP_001269354 NM_006572 NP_006563 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. |
Subcellular Location | Membrane; Lipid-anchor. Melanosome. Cytoplasm. Nucleus. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Detected in the cytoplasm of Leydig cells and in the seminiferous epithelium, including differentiating cells from the spermatogonia to mature spermatozoa stages. In round spermatids, also present in the nuclei. |
Tissue Specificity | Expressed in testis, including in Leydig cells and in the seminiferous epithelium, in differentiating cells from the spermatogonia to mature spermatozoa stages and round spermatids (at protein level). Expressed in 99.2% of spermatozoa from healthy individuals, but only in 28.6% of macrocephalic spermatozoa from infertile patients (at protein level). {ECO:0000269|PubMed:18703424}. |
Top Pathways | Long-term depression, Vascular smooth muscle contraction, cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Regulation of actin cytoskeleton |
G α 13 (A-20) - sc-410 from Santa Cruz Biotechnology
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G α 13 (C-13) - sc-26788 from Santa Cruz Biotechnology
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G α 13 (G-15) - sc-26787 from Santa Cruz Biotechnology
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G α 13 (H-57) - sc-292723 from Santa Cruz Biotechnology
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Anti-G protein alpha 13 antibody - ab193552 from Abcam
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Anti-G protein alpha 13 antibody - ab130689 from Abcam
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Anti-G protein alpha 13 antibody - ab56937 from Abcam
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Anti-G protein alpha 13 antibody [1H8H6] - ab170066 from Abcam
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Anti-G protein alpha 13 antibody [EPR5436] - ab128900 from Abcam
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Anti-G protein alpha 13 antibody - N-terminal - ab135319 from Abcam
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Anti-GNA13 Antibody (aa184-212, AP) - LS-C214763 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa184-212, APC) - LS-C214764 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa184-212, Biotin) - LS-C214765 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa39-88) - LS-C152169 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa184-212, PE) - LS-C214767 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa184-212, FITC) - LS-C214766 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa184-212, Azide-free, HRP) - LS-C214768 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa183-212) - LS-C321673 from LifeSpan Bioscience
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Anti-GNA13 Antibody (clone 6F6-B5) - LS-C307705 from LifeSpan Bioscience
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Anti-GNA13 Antibody (N-Terminus) - LS-C169774 from LifeSpan Bioscience
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Anti-GNA13 Antibody - LS-C341844 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa184-212) - LS-C166541 from LifeSpan Bioscience
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Anti-GNA13 Antibody (Internal, clone EPR5436) IHC-plus™ - LS-B9316 from LifeSpan Bioscience
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Anti-GNA13 Antibody - LS-C334259 from LifeSpan Bioscience
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Anti-GNA13 Antibody (aa1-378) - LS-C36521 from LifeSpan Bioscience
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