| Gene Symbol |
UBE2J1
|
| Entrez Gene |
51465
|
| Alt Symbol |
CGI-76, HSPC153, HSPC205, HSU93243, NCUBE-1, NCUBE1, UBC6, UBC6E, Ubc6p
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin-conjugating enzyme E2, J1
|
| Other Description |
HSUBC6e|non-canonical ubiquitin-conjugating enzyme 1|ubiquitin-conjugating enzyme E2 J1|ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)|ubiquitin-conjugating enzyme E2, J1, U|yeast ubiquitin-conjugating enzyme UBC6 homolog E
|
| Swissprots |
Q9UF10 Q9P011 Q5W0N4 A8K3F9 Q53F25 Q9NY66 Q9P0S0 Q9NQL3 Q9BZ32 Q9Y385
|
| Accessions |
EAW48555 EAW48556 Q9Y385 AB075487 AF151039 AAF36125 AF151834 AAD34071 AF161502 AAF29117 AJ245898 CAB83212 AJ420479 AJ420522 AJ420578 AJ420600 AK223464 BAD97184 AK290574 BAF83263 AK300629 BAG62320 BC013973 AAH13973 BF058850 DQ895144 ABM86070 EU176317 ABW03768 U93243 AAF21505 XM_011535887 XP_011534189 XM_011535888 XP_011534190 NM_016021 NP_057105
|
| Function |
Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). {ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000269|PubMed:12082160, ECO:0000269|PubMed:22607976}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:12082160}; Single-pass type IV membrane protein {ECO:0000269|PubMed:12082160}.
|
| Top Pathways |
Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum
|
![Western Blot: UBE2J1 Overexpression Lysate (Adult Normal) [NBL1-17534] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UBE2J1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4343_UBE2J1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17534-img0002.jpg)