Gene Symbol | PGLYRP3 |
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Entrez Gene | 114771 |
Alt Symbol | PGLYRPIalpha, PGRP-Ialpha, PGRPIA |
Species | Human |
Gene Type | protein-coding |
Description | peptidoglycan recognition protein 3 |
Other Description | peptidoglycan recognition protein I alpha|peptidoglycan recognition protein intermediate alpha |
Swissprots | A1A4U8 Q5SY65 Q96LB9 |
Accessions | EAW53338 Q96LB9 AY035376 AAK72484 BC069741 AAH69741 BC069798 AAH69798 BC069801 AAH69801 BC128114 AAI28115 BC128115 AAI28116 HQ447482 ADQ31968 XM_011509118 XP_011507420 XM_011509119 XP_011507421 XM_011509120 XP_011507422 XR_921736 NM_052891 NP_443123 |
Function | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. {ECO:0000269|PubMed:16354652}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:16354652}. |
Tissue Specificity | Detected in skin epidermis, eccrine sweat glands and ducts, ciliary body epithelial cells of the eye, in small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). Highly expressed in skin and esophagus, expressed also in tonsils and thymus and to a much lesser extent in the stomach, descending colon, rectum and brain. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:16354652}. |
PGRP-Iα (K-15) - sc-54969 from Santa Cruz Biotechnology
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PGRP-Iα (187C434) - sc-52946 from Santa Cruz Biotechnology
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Anti-PGRP1A antibody - ab118473 from Abcam
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Anti-PGRP1A antibody [187C434] - ab13901 from Abcam
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Anti-PGLYRP3 Antibody (aa178-193) - LS-C90063 from LifeSpan Bioscience
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Anti-PGLYRP3 Antibody (aa61-110) - LS-C152180 from LifeSpan Bioscience
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Anti-PGLYRP3 Antibody (aa178-193) - LS-C19360 from LifeSpan Bioscience
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Anti-PGLYRP3 Antibody (aa45-288) - LS-C178621 from LifeSpan Bioscience
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PGLYRP3/PGRPIA Antibody (187C434) - NB100-56729 from Novus Biologicals
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PGLYRP3/PGRPIA Antibody - NBP1-80919 from Novus Biologicals
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PGLYRP3/PGRPIA Antibody (187C434) [Azide Free] - NBP2-33249 from Novus Biologicals
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Anti-PGLYRP3 antibody produced in rabbit - HPA030369 from Sigma-Aldrich
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PGLYRP3 Antibody - N-terminal region (ARP66426_P050) - ARP66426_P050 from Aviva Systems Biology
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PGLYRP3 antibody - orb77994 from Biorbyt
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PGLYRP3 antibody - 70R-19243 from Fitzgerald
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PGLYRP3 Antibody - abx037060 from Abbexa
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PGLYRP3 antibody - 18082-1-AP from Acris Antibodies
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PGLYRP3 antibody - MAB0068 from Acris Antibodies
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PGLYRP3 antibody - 18082-1-AP from Proteintech Group
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peptidoglycan recognition protein 3 , Polyclonal Antibody - MBS710918 from MyBioSource
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PGLYRP3 Antibody - 39601 from Signalway Antibody
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PGLYRP3 Antibody - E305474 from Enogene
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Anti-PGLYRP3 (aa 45-288) polyclonal antibody - DPABH-09053 from Creative Diagnostics
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PGRP-1a Monoclonal Antibody (187C434) - MA1-41125 from Thermo Fisher Scientific
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PGLYRP3, Polyclonal Antibody - MBS415820 from MyBioSource
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