| Gene Symbol |
CNTNAP1
|
| Entrez Gene |
8506
|
| Alt Symbol |
CASPR, CNTNAP, NRXN4, P190
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
contactin associated protein 1
|
| Other Description |
caspr1|contactin-associated protein 1|neurexin IV|neurexin-4
|
| Swissprots |
P78357
|
| Accessions |
CCQ43225 EAW60867 EAW60868 EAW60869 P78357 BC160132 AAI60132 BC171797 BU729460 U87223 AAB48481 XM_005257748 XP_005257805 NM_003632 NP_003623
|
| Function |
Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis.
|
| Top Pathways |
Cell adhesion molecules (CAMs)
|