| Gene Symbol |
ZBTB14
|
| Entrez Gene |
7541
|
| Alt Symbol |
ZF5, ZFP-161, ZFP-5, ZFP161, ZNF478
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger and BTB domain containing 14
|
| Other Description |
ZFP161 zinc finger protein|zinc finger and BTB domain-containing protein 14|zinc finger protein 161 homolog|zinc finger protein 478|zinc finger protein 5 homolog|zinc finger protein homologous to Zfp161 in mouse
|
| Swissprots |
O00403 Q2TB80 O43829
|
| Accessions |
CAH05530 CAH25912 EAX01647 O43829 AK313236 BAG36047 AW338628 BC057282 BC110519 AAI10520 BI561601 D89859 BAA20131 DA817685 DB442630 EU446715 ABZ92244 Y12726 CAA73258 NM_001143823 NP_001137295 NM_001243702 NP_001230631 NM_001243704 NP_001230633 NM_003409 NP_003400
|
| Function |
Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'- CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters. {ECO:0000269|PubMed:17714511}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:15629158}. Note=Colocalizes with ZBTB21 in nucleus in HEK293 cells.
|
