Gene Symbol | ZBTB14 |
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Entrez Gene | 7541 |
Alt Symbol | ZF5, ZFP-161, ZFP-5, ZFP161, ZNF478 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger and BTB domain containing 14 |
Other Description | ZFP161 zinc finger protein|zinc finger and BTB domain-containing protein 14|zinc finger protein 161 homolog|zinc finger protein 478|zinc finger protein 5 homolog|zinc finger protein homologous to Zfp161 in mouse |
Swissprots | O00403 Q2TB80 O43829 |
Accessions | CAH05530 CAH25912 EAX01647 O43829 AK313236 BAG36047 AW338628 BC057282 BC110519 AAI10520 BI561601 D89859 BAA20131 DA817685 DB442630 EU446715 ABZ92244 Y12726 CAA73258 NM_001143823 NP_001137295 NM_001243702 NP_001230631 NM_001243704 NP_001230633 NM_003409 NP_003400 |
Function | Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'- CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters. {ECO:0000269|PubMed:17714511}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15629158}. Note=Colocalizes with ZBTB21 in nucleus in HEK293 cells. |
ZFP161 CRISPR/Cas9 KO Plasmid (h) - sc-407261 from Santa Cruz Biotechnology
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ZFP161 HDR Plasmid (h) - sc-407261-HDR from Santa Cruz Biotechnology
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ZFP161 Double Nickase Plasmid (h) - sc-407261-NIC from Santa Cruz Biotechnology
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ZFP161 Double Nickase Plasmid (h2) - sc-407261-NIC-2 from Santa Cruz Biotechnology
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ZFP161 CRISPR Activation Plasmid (h) - sc-407261-ACT from Santa Cruz Biotechnology
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ZFP161 CRISPR Activation Plasmid (h2) - sc-407261-ACT-2 from Santa Cruz Biotechnology
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ZFP161 Lentiviral Activation Particles (h) - sc-407261-LAC from Santa Cruz Biotechnology
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ZFP161 Lentiviral Activation Particles (h2) - sc-407261-LAC-2 from Santa Cruz Biotechnology
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ZFP161 siRNA (h) - sc-76958 from Santa Cruz Biotechnology
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ZFP161 shRNA Plasmid (h) - sc-76958-SH from Santa Cruz Biotechnology
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ZFP161 shRNA (h) Lentiviral Particles - sc-76958-V from Santa Cruz Biotechnology
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ZFP161 RNAi - H00007541-R01 from Novus Biologicals
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MISSION® esiRNA - EHU133881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23176 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23176 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09557 from Sigma-Aldrich
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ZBTB14 siRNA (Human) - CRH5152 from Cohesion Biosciences
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ZBTB14 - MBS8230276 from MyBioSource
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shRNA set against Human ZFP161 (NM_003409.4) - SHH450476 from Creative biogene
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ZBTB14 shRNA Plasmid (Human) - CHH5152 from Cohesion Biosciences
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ZFP161 miRNA 3'UTR clone - MiUTR3H-04681 from Creative biogene
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ZFP161 miRNA 3'UTR clone - MiUTR3H-04682 from Creative biogene
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