| Gene Symbol |
RABGEF1
|
| Entrez Gene |
282335
|
| Alt Symbol |
RABEX5
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
RAB guanine nucleotide exchange factor (GEF) 1
|
| Other Description |
Rab5 guanine nucleotide exchange factor Rabex-5|rab5 GDP/GTP exchange factor|rabex-5
|
| Swissprots |
O18973
|
| Accessions |
DAA15357 O18973 AJ001119 CAA04545 BC109491 AAI09492 NM_174591 NP_777016
|
| Function |
Rab effector protein acting as linker between gamma- adaptin and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. {ECO:0000269|PubMed:16462746, ECO:0000269|PubMed:9323142}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:9323142}. Early endosome {ECO:0000269|PubMed:9323142}. Recycling endosome {ECO:0000269|PubMed:9323142}.
|
| Tissue Specificity |
Detected in brain. {ECO:0000269|PubMed:9323142}.
|