Gene Symbol | RABGEF1 |
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Entrez Gene | 282335 |
Alt Symbol | RABEX5 |
Species | Bovine |
Gene Type | protein-coding |
Description | RAB guanine nucleotide exchange factor (GEF) 1 |
Other Description | Rab5 guanine nucleotide exchange factor Rabex-5|rab5 GDP/GTP exchange factor|rabex-5 |
Swissprots | O18973 |
Accessions | DAA15357 O18973 AJ001119 CAA04545 BC109491 AAI09492 NM_174591 NP_777016 |
Function | Rab effector protein acting as linker between gamma- adaptin and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. {ECO:0000269|PubMed:16462746, ECO:0000269|PubMed:9323142}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9323142}. Early endosome {ECO:0000269|PubMed:9323142}. Recycling endosome {ECO:0000269|PubMed:9323142}. |
Tissue Specificity | Detected in brain. {ECO:0000269|PubMed:9323142}. |
Recombinant Bovine Rab5 GDP/GTP exchange factor(RABGEF1) - CSB-YP019233BO CSB-EP019233BO CSB-BP019233BO CSB-MP019233BO from Cusabio
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Rab5 GDP/GTP exchange factor (RABGEF1), Recombinant Protein - MBS1036008 from MyBioSource
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