| Gene Symbol | RABGEF1 |
|---|---|
| Entrez Gene | 282335 |
| Alt Symbol | RABEX5 |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | RAB guanine nucleotide exchange factor (GEF) 1 |
| Other Description | Rab5 guanine nucleotide exchange factor Rabex-5|rab5 GDP/GTP exchange factor|rabex-5 |
| Swissprots | O18973 |
| Accessions | DAA15357 O18973 AJ001119 CAA04545 BC109491 AAI09492 NM_174591 NP_777016 |
| Function | Rab effector protein acting as linker between gamma- adaptin and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. {ECO:0000269|PubMed:16462746, ECO:0000269|PubMed:9323142}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9323142}. Early endosome {ECO:0000269|PubMed:9323142}. Recycling endosome {ECO:0000269|PubMed:9323142}. |
| Tissue Specificity | Detected in brain. {ECO:0000269|PubMed:9323142}. |