GBA3

Gene Symbol	GBA3
Entrez Gene	57733
Alt Symbol	CBG, CBGL1, GLUC, KLRP
Species	Human
Gene Type	protein-coding
Description	glucosidase, beta, acid 3 (gene/pseudogene)
Other Description	cytosolic beta-glucosidase|cytosolic beta-glucosidase-like protein 1|glucosidase, beta, acid 3 (cytosolic)|klotho-related protein
Swissprots	Q9H3T4 Q9H4C6 Q3MIH4 Q9H227 Q32LY7 Q8NHT8 Q53GG8 Q6NSF4
Accessions	EAW92802 EAW92803 Q9H227 AB017913 BAB18741 AF317840 AAG39217 AF323990 AAL37305 AJ278964 CAC08178 AK222963 BAD96683 AK292746 BAF85435 AK298377 BAH12772 AK313189 BAG36006 BC029362 AAH29362 BC070188 AAH70188 BC101829 AAI01830 BC109377 AAI09378 BC136264 AAI36265 BP383134 CB163648 NM_001128432 NP_001121904 NM_001277225 NP_001264154 NM_020973 NP_066024 NR_102355 NR_102356 NR_102357
Function	Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. {ECO:0000269|PubMed:11784319, ECO:0000269|PubMed:12594539, ECO:0000269|PubMed:17595169}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:12594539, ECO:0000269|PubMed:17595169}.
Tissue Specificity	Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas. {ECO:0000269|PubMed:11043382, ECO:0000269|PubMed:12594539}.
Top Pathways	Cyanoamino acid metabolism, Starch and sucrose metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GBA3 full length protein - ab187481 from Abcam Category Protein Source E. coli Species Human

Human GBA3 protein fragment - ab163648 from Abcam Category Protein Source Wheat germ Species Human

GBA3 / CBG Antibody Blocking Peptide - LS-E1550 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GBA3 / CBG Antibody Blocking Peptide - LS-E20993 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Cytosolic beta-Glucosidase/GBA3 Partial Recombinant Protein - H00057733-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

GBA3-Antibody-C-term-Blocking-peptide - BP12289b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Cytosolic beta-Glucosidase/GBA3, CF - 5969-GH-010 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Thr13-Leu469 with a C-terminal 6-His tag

Human GBA3 His tag protein - orb83824 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Insect Species Human

GBA3 Blocking Peptide - 33R-5474 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GBA3 fusion protein - ag9936 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GBA3 fusion protein - ag10114 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human GBA3, His tagged - GBA3-856H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human GBA3, His-tagged - GBA3-13175H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human glucosidase, beta, acid 3, His-tagged - GBA3-626H from Creative Biomart Category Protein Source E.coli Species Human

GBA3 / CBGL1 - PN201664 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Baculovirus Species Human

Human GBA3 / CBGL1 Protein (His Tag) - 11593-H08B-20 from Sino Biological Category Protein Prices $298.00, $298.00 Sizes 10 µg, 20 µg Source Baculovirus-Insect Cells Species Human

GBA3 Blocking Peptide - CBP3958 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Recombinant Human Cytosolic beta-glucosidase(GBA3) - CSB-YP884446HU CSB-EP884446HU CSB-BP884446HU CSB-MP884446HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GBA3, 1-469aa, Human, His tag, E.coli - ATGP2849 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Human Cytosolic beta-Glucosidase/GBA3, CF - 5969-GH from R&D Systems Category Protein Prices $329.00 Sizes 10 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Thr13-Leu469 with a C-terminal 6-His tag Species Human

GBA3 Protein - abx163646 from Abbexa Category Protein Species Human

Cytosolic beta-glucosidase (transcript variant 1) - TP311035 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human GBA3 / CBGL1 Protein (His tag) - PKSH031073 from Elabscience Category Protein Source Baculoviru Species Human

Recombinant Human GBA3 protein, His-tagged - GBA3-174H from Creative Biomart Category Protein Source Insect cells Species Human

GBA3 Blocking Peptide - abx162451 from Abbexa Category Peptide Species Human

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