EIF4EBP2

Gene Symbol	EIF4EBP2
Entrez Gene	1979
Alt Symbol	4EBP2, PHASII
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E binding protein 2
Other Description	4E-BP2|eIF4E-binding protein 2|eukaryotic translation initiation factor 4E-binding protein 2|phosphorylated, heat and acid stable regulated by insulin protein II
Swissprots	Q13542
Accessions	CAT01881 EAW54400 EAW54401 EAW54402 Q13542 AK001936 AK057643 AK313724 BAG36466 BC005057 AAH05057 BC015007 BC050633 AAH50633 BG717474 BT007317 AAP35981 CR542240 CAG47036 CR627373 DQ583065 DQ893105 ABM84031 DQ896377 ABM87376 L36056 AAA62270 NM_004096 NP_004087
Function	Repressor of translation initiation involved in synaptic plasticity, learning and memory formation (By similarity). Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (PubMed:25533957). EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal stem cell renewal via its ability to repress translation initiation (By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (By similarity). {ECO:0000250|UniProtKB:P70445, ECO:0000269|PubMed:25533957}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-EIF4EBP2-cDNA-Clone - DC01608 from Abgent, a WuXi AppTec company Prices $162.00 Sizes 10 µg Species Human Accession BC005057

EIF4EBP2 - MBS1271203 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC005057

Human EIF4EBP2 ORF Clone(NM_004096.4) - CDCL162178 from Creative Biomart Species Human Accession NM_004096.4

Human EIF4EBP2 Gene ORF cDNA clone in cloning vector - HG14489-G from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14489-CY from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14489-NF from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14489-CF from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14489-NM from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14489-CM from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14489-NH from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14489-ANG from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14489-NY from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14489-ACG from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14489-G-H from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14489-CH from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid - HG14489-UT from Sino Biological Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14489-ANR from Sino Biological Species Human

Human EIF4EBP2 ORF Clone (BC005057) - CDCS411606 from Creative biogene Species Human Accession Q13542

Human EIF4EBP2 ORF clone (BC005057) - CDCB159079 from Creative biogene Species Human

Human 4E-BP2 cDNA Clone - orb143006 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human EIF4EBP2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14489-ACR from Sino Biological Species Human

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