EIF4EBP2

Gene Symbol	EIF4EBP2
Entrez Gene	1979
Alt Symbol	4EBP2, PHASII
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E binding protein 2
Other Description	4E-BP2|eIF4E-binding protein 2|eukaryotic translation initiation factor 4E-binding protein 2|phosphorylated, heat and acid stable regulated by insulin protein II
Swissprots	Q13542
Accessions	CAT01881 EAW54400 EAW54401 EAW54402 Q13542 AK001936 AK057643 AK313724 BAG36466 BC005057 AAH05057 BC015007 BC050633 AAH50633 BG717474 BT007317 AAP35981 CR542240 CAG47036 CR627373 DQ583065 DQ893105 ABM84031 DQ896377 ABM87376 L36056 AAA62270 NM_004096 NP_004087
Function	Repressor of translation initiation involved in synaptic plasticity, learning and memory formation (By similarity). Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (PubMed:25533957). EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal stem cell renewal via its ability to repress translation initiation (By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (By similarity). {ECO:0000250|UniProtKB:P70445, ECO:0000269|PubMed:25533957}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human eIF4EBP2 full length protein - ab104667 from Abcam Category Protein Source E. coli Species Human

Human eIF4EBP2 full length protein - ab172157 from Abcam Category Protein Source E. coli Species Human

4E-BP2 / EIF4EBP2 Antibody Blocking Peptide - LS-E18673 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

eIF4EBP2 Recombinant Protein - H00001979-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

eIF4EBP2 Partial Recombinant Protein - H00001979-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human eIF4EBP2 Protein - NBP1-51034 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

EIF4EBP2 Protein (OPPA00105) - OPPA00105 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human 4E-BP2 protein - orb168286 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human 4E-BP2 protein - orb245819 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human 4E-BP2 protein - orb246335 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

EIF4EBP2 protein (His tag) - 80R-1722 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

4E-BP2 (1-120, His-tag) - AR09904PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

4E-BP2 (1-120, His-tag) - AR09904PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

4E-BP2 - H00001979-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

4E-BP2 - H00001979-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

4E-BP2 - H00001979-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

4E-BP2, EIF4EBP2, Human, Recombinant - 19-CE61 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

EIF4EBP2, 1-120aa, Human, His tag, E.coli - 01-P0964 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

EIF4EBP2 fusion protein - ag1670 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

EIF4EBP2 fusion protein - ag8101 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

EIF4EBP2 fusion protein - ag8172 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human EIF4EBP2 Protein - BP001964-CE61 from Syd Labs Category Protein Prices $180.00, $528.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human EIF4EBP2 Protein - BP001964-PRO-176 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 50 µg, 1 mg Source E. coli-derived. Species Human

EIF4EBP2, 1-120aa, Recombinant Protein - GWB-P1074H from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

EIF4EBP2 Human Protein - GWB-BSP472 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

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