CACNB4

Gene Symbol CACNB4
Entrez Gene 785
Alt Symbol CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6
Species Human
Gene Type protein-coding
Description calcium channel, voltage-dependent, beta 4 subunit
Other Description calcium channel voltage-dependent subunit beta 4|dihydropyridine-sensitive L-type, calcium channel beta-4 subunit|voltage-dependent L-type calcium channel subunit beta-4
Swissprots O60515 Q96L40 B4DG40 A7BJ74 Q6B000 A8K1Y4 O00305
Accessions AAF61674 AAX82014 AAY14711 AAY14759 EAX11493 EAX11494 O00305 AB302276 BAF73808 AF038852 AAC24206 AF075047 AK290049 BAF82738 AK291378 BAF84067 AK294398 BAG57651 AK316045 BAH14416 AL700210 AY054985 AAL14351 BC075049 AAH75049 BP229182 BP360802 BX279713 BX484858 BX648679 DA782833 HQ214056 ADP09414 T23939 U95020 AAB53333 XM_005246838 XP_005246895 XM_006712731 XP_006712794 XM_011511795 XP_011510097 XM_011511796 XP_011510098 XM_011511797 XP_011510099 XM_011511798 XP_011510100 XM_011511799 XP_011510101 XM_011511800 XP_011510102 XR_923022 XR_923023 NM_000726 NP_000717 NM_001005746 NP_001005746 NM_001005747 NP_001005747 NM_001145798 NP_001139270
Function The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Tissue Specificity Expressed predominantly in the cerebellum and kidney.
Top Pathways MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

L-type Ca ++ CP β4 (L-16) - sc-54588 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
L-type Ca<sup>++</sup> CP β4 (L-16): sc-54588. Western blot analysis of L-type Ca<sup>++</sup> CP β4 expression in non-transfected: sc-117752 (A) and mouse L-type Ca<sup>++</sup> CP β4 transfected: sc-127077 (B) 293T whole cell lysates.

L-type Ca ++ CP β4 (S-19) - sc-54589 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
L-type Ca<sup>++</sup> CP β4 (S-19): sc-54589. Western blot analysis of L-type Ca<sup>++</sup> CP β4 expression in non-transfected: sc-117752 (A) and mouse L-type Ca<sup>++</sup> CP β4 transfected: sc-127077 (B) 293T whole cell lysates.

Anti-CACNB4 antibody - ab26060 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-CACNB4 antibody (ab26060) at 0.2 µg/ml + Human Bone Marrow lysate (35µg protein in RIPA buffer).

Anti-CACNB4 antibody - ab171783 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CACNB4 antibody (ab171783) at 1 µg/mlLane 1 : CACNB4 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 15 µl per lane.

Anti-CACNB4 antibody [S10-7] - ab85788 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7
Overlay histogram showing SH-SH5Y cells stained with ab85788 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab85788, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in SH-SY5Y cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-CACNB4 antibody - C-terminal - ab151500 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CACNB4 antibody - C-terminal (ab151500) at 1/1000 dilution + Mouse cerebellum whole cell lysate at 50 µg

Anti-CACNB4 Antibody (aa458-474, clone S10-7, Atto 565) - LS-C227665 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, Atto 655) - LS-C227668 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, Atto 633) - LS-C227667 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, Atto 680) - LS-C227669 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, Atto 700) - LS-C227670 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, Atto 594) - LS-C227666 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa508-520) - LS-C54599 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.2 ug/ml) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CACNB4 Antibody (aa458-474, clone S10-7, AP) - LS-C227671 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, APC) - LS-C227672 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa250-300) - LS-C110198 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CACNB4 antibody LS-C110198 Western blot of MCF7 cell lysate.

Anti-CACNB4 Antibody (clone 7E1) - LS-C196802 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7E1
CACNB4 monoclonal antibody (M01), clone 7E1. Western Blot analysis of CACNB4 expression in K-562.

Anti-CACNB4 Antibody (aa458-474, clone S10-7, Biotin) - LS-C227673 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7) - LS-C109017 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7
CavBeta4 (S10-7), Human Hippocampus.

Anti-CACNB4 Antibody (aa458-474, clone S10-7, FITC) - LS-C227674 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, PE, Atto 594) - LS-C227676 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, RPE) - LS-C227678 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, SA) - LS-C227679 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody (aa458-474, clone S10-7, PerCP) - LS-C227677 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S10-7

Anti-CACNB4 Antibody - LS-C306694 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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