Gene Symbol | CACNB4 |
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Entrez Gene | 785 |
Alt Symbol | CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6 |
Species | Human |
Gene Type | protein-coding |
Description | calcium channel, voltage-dependent, beta 4 subunit |
Other Description | calcium channel voltage-dependent subunit beta 4|dihydropyridine-sensitive L-type, calcium channel beta-4 subunit|voltage-dependent L-type calcium channel subunit beta-4 |
Swissprots | O60515 Q96L40 B4DG40 A7BJ74 Q6B000 A8K1Y4 O00305 |
Accessions | AAF61674 AAX82014 AAY14711 AAY14759 EAX11493 EAX11494 O00305 AB302276 BAF73808 AF038852 AAC24206 AF075047 AK290049 BAF82738 AK291378 BAF84067 AK294398 BAG57651 AK316045 BAH14416 AL700210 AY054985 AAL14351 BC075049 AAH75049 BP229182 BP360802 BX279713 BX484858 BX648679 DA782833 HQ214056 ADP09414 T23939 U95020 AAB53333 XM_005246838 XP_005246895 XM_006712731 XP_006712794 XM_011511795 XP_011510097 XM_011511796 XP_011510098 XM_011511797 XP_011510099 XM_011511798 XP_011510100 XM_011511799 XP_011510101 XM_011511800 XP_011510102 XR_923022 XR_923023 NM_000726 NP_000717 NM_001005746 NP_001005746 NM_001005747 NP_001005747 NM_001145798 NP_001139270 |
Function | The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
Tissue Specificity | Expressed predominantly in the cerebellum and kidney. |
Top Pathways | MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
CACNB4 peptide (508-520) - ab45660 from Abcam
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Human CACNB4 full length protein - ab132320 from Abcam
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Human CACNB4 protein fragment - ab116908 from Abcam
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CACNB4 Antibody Blocking Peptide - LS-E25806 from LifeSpan Bioscience
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CACNB4 Antibody Blocking Peptide - LS-E13178 from LifeSpan Bioscience
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CACNB4 Antibody Blocking Peptide - LS-E26220 from LifeSpan Bioscience
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CACNB4 Antibody Blocking Peptide - LS-E12452 from LifeSpan Bioscience
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Recombinant Human CACNB4 Protein - H00000785-P01 from Novus Biologicals
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CACNB4 Partial Recombinant Protein - H00000785-Q01 from Novus Biologicals
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Cav beta 4 (C terminus) blocking peptide - GTX89641-PEP from GeneTex
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Cav beta 4 (internal) blocking peptide - GTX89203-PEP from GeneTex
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CACNB4 Immunizing peptide - orb17135 from Biorbyt
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CACNB4 Blocking Peptide - 33R-4882 from Fitzgerald
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CACNB4 Blocking Peptide - 33R-3649 from Fitzgerald
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CACNB4 Peptide - AC21-0637-P from Abcore
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CACNB4 Peptide - AC21-1051-P from Abcore
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CACNB4 - H00000785-P01-10 from Acris Antibodies
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CACNB4 - H00000785-P01-25 from Acris Antibodies
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CACNB4 - H00000785-Q01-10 from Acris Antibodies
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CACNB4 - H00000785-Q01-25 from Acris Antibodies
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CACNB4 Peptide - 45-352P from ProSci
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CACNB4 Peptide - 45-351P from ProSci
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CACNB4 fusion protein - Ag12996 from Proteintech Group
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CACNB4 fusion protein - ag12178 from Proteintech Group
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Recombinant Human CACNB4, His-tagged - CACNB4-10640H from Creative Biomart
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