| Gene Symbol | WNT7B |
|---|---|
| Entrez Gene | 7477 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | wingless-type MMTV integration site family, member 7B |
| Other Description | protein Wnt-7b |
| Swissprots | Q96Q12 P56706 B8A596 |
| Accessions | CAI38649 EAW73394 P56706 AB062766 BAB68399 AF416743 AAN32640 AK123019 AK289526 BAF82215 BC034923 AAH34923 BM047487 CB853639 EU831473 ACE87160 EU831560 ACE86479 HQ447633 ADQ32118 XM_011530366 XP_011528668 NM_058238 NP_478679 |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate. |
| Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |