| Gene Symbol |
WNT7B
|
| Entrez Gene |
7477
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
wingless-type MMTV integration site family, member 7B
|
| Other Description |
protein Wnt-7b
|
| Swissprots |
Q96Q12 P56706 B8A596
|
| Accessions |
CAI38649 EAW73394 P56706 AB062766 BAB68399 AF416743 AAN32640 AK123019 AK289526 BAF82215 BC034923 AAH34923 BM047487 CB853639 EU831473 ACE87160 EU831560 ACE86479 HQ447633 ADQ32118 XM_011530366 XP_011528668 NM_058238 NP_478679
|
| Function |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Tissue Specificity |
Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate.
|
| Top Pathways |
Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection
|
![Western Blot: Wnt7b Overexpression Lysate (Adult Normal) [NBL1-17877] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Wnt7b.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4245_Wnt7b%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17877-img0002.jpg)