Gene Symbol | WNT7B |
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Entrez Gene | 7477 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family, member 7B |
Other Description | protein Wnt-7b |
Swissprots | Q96Q12 P56706 B8A596 |
Accessions | CAI38649 EAW73394 P56706 AB062766 BAB68399 AF416743 AAN32640 AK123019 AK289526 BAF82215 BC034923 AAH34923 BM047487 CB853639 EU831473 ACE87160 EU831560 ACE86479 HQ447633 ADQ32118 XM_011530366 XP_011528668 NM_058238 NP_478679 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate. |
Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |
Wnt-7b CRISPR/Cas9 KO Plasmid (h) - sc-401626 from Santa Cruz Biotechnology
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Wnt-7b HDR Plasmid (h) - sc-401626-HDR from Santa Cruz Biotechnology
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Wnt-7b Double Nickase Plasmid (h) - sc-401626-NIC from Santa Cruz Biotechnology
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Wnt-7b Double Nickase Plasmid (h2) - sc-401626-NIC-2 from Santa Cruz Biotechnology
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Wnt-7b CRISPR Activation Plasmid (h) - sc-401626-ACT from Santa Cruz Biotechnology
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Wnt-7b CRISPR Activation Plasmid (h2) - sc-401626-ACT-2 from Santa Cruz Biotechnology
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Wnt-7b Lentiviral Activation Particles (h) - sc-401626-LAC from Santa Cruz Biotechnology
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Wnt-7b Lentiviral Activation Particles (h2) - sc-401626-LAC-2 from Santa Cruz Biotechnology
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Wnt-7b siRNA (h) - sc-41116 from Santa Cruz Biotechnology
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Wnt-7b shRNA Plasmid (h) - sc-41116-SH from Santa Cruz Biotechnology
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Wnt-7b shRNA (h) Lentiviral Particles - sc-41116-V from Santa Cruz Biotechnology
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Wnt-7b RNAi - H00007477-R01 from Novus Biologicals
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MISSION® esiRNA - EHU119001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1325 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1325 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08036 from Sigma-Aldrich
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WNT7B siRNA (Human) - CRH5116 from Cohesion Biosciences
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WNT7B - MBS8224356 from MyBioSource
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shRNA set against Human WNT7B (NM_058238.2) - SHH447364 from Creative biogene
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Human WNT7B siRNA - orb265618 from Biorbyt
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WNT7B shRNA Plasmid (Human) - CHH5116 from Cohesion Biosciences
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WNT7B miRNA 3'UTR clone - MiUTR4H-TG12781 from Creative biogene
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