| Gene Symbol |
ST6GALNAC3
|
| Entrez Gene |
256435
|
| Alt Symbol |
PRO7177, SIAT7C, ST6GALNACIII, STY
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
|
| Other Description |
GalNAc alpha-2,6-sialyltransferase III|SIAT7-C|ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltran|ST6GALNAC III|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase III|sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) C|sialyltransferase 7C
|
| Swissprots |
Q6UX29 Q8NDV1 Q6PCE0 Q8N259
|
| Accessions |
EAX06388 EAX06389 Q8NDV1 AJ507291 CAD45371 AK023731 AK091215 BAC03611 AK130749 AK297363 BAG59810 AY358540 AAQ88904 BC039520 BC059363 AAH59363 BX648274 DA800675 DB473741 HQ448501 ADQ32981 XM_006710553 XP_006710616 NM_001160011 NP_001153483 NM_152996 NP_694541
|
| Function |
Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. ST6GalNAcIII prefers glycolipids to glycoproteins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Top Pathways |
Glycosphingolipid biosynthesis - ganglio series
|
