Gene Symbol | ST6GALNAC3 |
---|---|
Entrez Gene | 256435 |
Alt Symbol | PRO7177, SIAT7C, ST6GALNACIII, STY |
Species | Human |
Gene Type | protein-coding |
Description | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 |
Other Description | GalNAc alpha-2,6-sialyltransferase III|SIAT7-C|ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltran|ST6GALNAC III|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase III|sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) C|sialyltransferase 7C |
Swissprots | Q6UX29 Q8NDV1 Q6PCE0 Q8N259 |
Accessions | EAX06388 EAX06389 Q8NDV1 AJ507291 CAD45371 AK023731 AK091215 BAC03611 AK130749 AK297363 BAG59810 AY358540 AAQ88904 BC039520 BC059363 AAH59363 BX648274 DA800675 DB473741 HQ448501 ADQ32981 XM_006710553 XP_006710616 NM_001160011 NP_001153483 NM_152996 NP_694541 |
Function | Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. ST6GalNAcIII prefers glycolipids to glycoproteins (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Top Pathways | Glycosphingolipid biosynthesis - ganglio series |
Sialyltransferase 7C CRISPR/Cas9 KO Plasmid (h) - sc-415238 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C HDR Plasmid (h) - sc-415238-HDR from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C Double Nickase Plasmid (h) - sc-415238-NIC from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C Double Nickase Plasmid (h2) - sc-415238-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C CRISPR Activation Plasmid (h) - sc-415238-ACT from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C CRISPR Activation Plasmid (h2) - sc-415238-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C Lentiviral Activation Particles (h) - sc-415238-LAC from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C Lentiviral Activation Particles (h2) - sc-415238-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C siRNA (h) - sc-63018 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C shRNA Plasmid (h) - sc-63018-SH from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7C shRNA (h) Lentiviral Particles - sc-63018-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU020231 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20664 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20664 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10962 from Sigma-Aldrich
|
||||||||
ST6GALNAC3 siRNA (Human) - CRJ6758 from Cohesion Biosciences
|
||||||||
ST6GALNAC3 - MBS8205151 from MyBioSource
|
||||||||
shRNA set against Human ST6GALNAC3 (NM_152996.2) - SHH418932 from Creative biogene
|
||||||||
Human ST6GALNAC3 siRNA - orb277259 from Biorbyt
|
||||||||
ST6GALNAC3 shRNA Plasmid (Human) - CHJ6758 from Cohesion Biosciences
|
||||||||
ST6GALNAC3 miRNA 3'UTR clone - MiUTR3H-11046 from Creative biogene
|