| Gene Symbol | FABP2 |
|---|---|
| Entrez Gene | 2169 |
| Alt Symbol | FABPI, I-FABP |
| Species | Human |
| Gene Type | protein-coding |
| Description | fatty acid binding protein 2, intestinal |
| Other Description | fatty acid-binding protein 2|fatty acid-binding protein, intestinal|intestinal-type fatty acid-binding protein |
| Swissprots | P12104 Q2NKJ1 |
| Accessions | AAA52417 EAW73666 P12104 AK025079 BC069466 AAH69466 BC069617 AAH69617 BC069625 AAH69625 BC069637 AAH69637 BC111791 AAI11792 HQ448385 ADQ32865 NM_000134 NP_000125 |
| Function | FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. |
| Subcellular Location | Cytoplasm. |
| Tissue Specificity | Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. {ECO:0000269|PubMed:14563446}. |
| Top Pathways | PPAR signaling pathway, Fat digestion and absorption |