| Gene Symbol |
FABP2
|
| Entrez Gene |
2169
|
| Alt Symbol |
FABPI, I-FABP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
fatty acid binding protein 2, intestinal
|
| Other Description |
fatty acid-binding protein 2|fatty acid-binding protein, intestinal|intestinal-type fatty acid-binding protein
|
| Swissprots |
P12104 Q2NKJ1
|
| Accessions |
AAA52417 EAW73666 P12104 AK025079 BC069466 AAH69466 BC069617 AAH69617 BC069625 AAH69625 BC069637 AAH69637 BC111791 AAI11792 HQ448385 ADQ32865 NM_000134 NP_000125
|
| Function |
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. {ECO:0000269|PubMed:14563446}.
|
| Top Pathways |
PPAR signaling pathway, Fat digestion and absorption
|
![Western Blot: intestinal FABP Overexpression Lysate (Adult Normal) [NBL1-10418] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for intestinal FABP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5323_intestinal%2520FABP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10418-img0002.jpg)