Gene Symbol | FABP2 |
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Entrez Gene | 2169 |
Alt Symbol | FABPI, I-FABP |
Species | Human |
Gene Type | protein-coding |
Description | fatty acid binding protein 2, intestinal |
Other Description | fatty acid-binding protein 2|fatty acid-binding protein, intestinal|intestinal-type fatty acid-binding protein |
Swissprots | P12104 Q2NKJ1 |
Accessions | AAA52417 EAW73666 P12104 AK025079 BC069466 AAH69466 BC069617 AAH69617 BC069625 AAH69625 BC069637 AAH69637 BC111791 AAI11792 HQ448385 ADQ32865 NM_000134 NP_000125 |
Function | FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. {ECO:0000269|PubMed:14563446}. |
Top Pathways | PPAR signaling pathway, Fat digestion and absorption |
I-FABP CRISPR/Cas9 KO Plasmid (h) - sc-416794 from Santa Cruz Biotechnology
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I-FABP HDR Plasmid (h) - sc-416794-HDR from Santa Cruz Biotechnology
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I-FABP Double Nickase Plasmid (h) - sc-416794-NIC from Santa Cruz Biotechnology
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I-FABP Double Nickase Plasmid (h2) - sc-416794-NIC-2 from Santa Cruz Biotechnology
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I-FABP CRISPR Activation Plasmid (h) - sc-416794-ACT from Santa Cruz Biotechnology
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I-FABP CRISPR Activation Plasmid (h2) - sc-416794-ACT-2 from Santa Cruz Biotechnology
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I-FABP Lentiviral Activation Particles (h) - sc-416794-LAC from Santa Cruz Biotechnology
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I-FABP Lentiviral Activation Particles (h2) - sc-416794-LAC-2 from Santa Cruz Biotechnology
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I-FABP siRNA (h) - sc-41239 from Santa Cruz Biotechnology
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I-FABP shRNA Plasmid (h) - sc-41239-SH from Santa Cruz Biotechnology
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I-FABP shRNA (h) Lentiviral Particles - sc-41239-V from Santa Cruz Biotechnology
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FABP2/I-FABP RNAi - H00002169-R01 from Novus Biologicals
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MISSION® esiRNA - EHU054151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8081 from Sigma-Aldrich
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FABP2 siRNA (Human) - CRH1509 from Cohesion Biosciences
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FABP2 - MBS8233081 from MyBioSource
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shRNA set against Human FABP2 (NM_000134.3) - SHH288605 from Creative biogene
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Human FABP2 siRNA - orb262011 from Biorbyt
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FABP2 shRNA Plasmid (Human) - CHH1509 from Cohesion Biosciences
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