Gene Symbol |
ACRBP
|
Entrez Gene |
84519
|
Alt Symbol |
CT23, OY-TES-1, SP32
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
acrosin binding protein
|
Other Description |
acrosin-binding protein|cancer/testis antigen 23|cancer/testis antigen OY-TES-1|proacrosin binding protein sp32
|
Swissprots |
Q9BY87 Q8NEB7
|
Accessions |
EAW88774 Q8NEB7 AB051833 BAB39388 AF085884 AK302290 BAG63630 AK311572 AK312782 BAG35645 BC033010 AAH33010 DQ890872 ABM81798 DQ894028 ABM84954 NM_032489 NP_115878
|
Function |
May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. {ECO:0000250}.
|
Subcellular Location |
Secreted {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Note=Colocalizes with proacrosin in the acrosome of sperm. {ECO:0000250}.
|
Tissue Specificity |
Expression restricted to testis in normal tissue. Expressed in a wide spectrum of cancers, including bladder, breast, liver, lung and colon cancers. {ECO:0000269|PubMed:11248070}.
|