Gene Symbol | ACRBP |
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Entrez Gene | 84519 |
Alt Symbol | CT23, OY-TES-1, SP32 |
Species | Human |
Gene Type | protein-coding |
Description | acrosin binding protein |
Other Description | acrosin-binding protein|cancer/testis antigen 23|cancer/testis antigen OY-TES-1|proacrosin binding protein sp32 |
Swissprots | Q9BY87 Q8NEB7 |
Accessions | EAW88774 Q8NEB7 AB051833 BAB39388 AF085884 AK302290 BAG63630 AK311572 AK312782 BAG35645 BC033010 AAH33010 DQ890872 ABM81798 DQ894028 ABM84954 NM_032489 NP_115878 |
Function | May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Note=Colocalizes with proacrosin in the acrosome of sperm. {ECO:0000250}. |
Tissue Specificity | Expression restricted to testis in normal tissue. Expressed in a wide spectrum of cancers, including bladder, breast, liver, lung and colon cancers. {ECO:0000269|PubMed:11248070}. |
OY-TES-1 CRISPR/Cas9 KO Plasmid (h) - sc-407850 from Santa Cruz Biotechnology
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OY-TES-1 HDR Plasmid (h) - sc-407850-HDR from Santa Cruz Biotechnology
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OY-TES-1 Double Nickase Plasmid (h) - sc-407850-NIC from Santa Cruz Biotechnology
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OY-TES-1 Double Nickase Plasmid (h2) - sc-407850-NIC-2 from Santa Cruz Biotechnology
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OY-TES-1 CRISPR Activation Plasmid (h) - sc-407850-ACT from Santa Cruz Biotechnology
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OY-TES-1 CRISPR Activation Plasmid (h2) - sc-407850-ACT-2 from Santa Cruz Biotechnology
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OY-TES-1 Lentiviral Activation Particles (h) - sc-407850-LAC from Santa Cruz Biotechnology
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OY-TES-1 Lentiviral Activation Particles (h2) - sc-407850-LAC-2 from Santa Cruz Biotechnology
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OY-TES-1 siRNA (h) - sc-95804 from Santa Cruz Biotechnology
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OY-TES-1 shRNA Plasmid (h) - sc-95804-SH from Santa Cruz Biotechnology
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OY-TES-1 shRNA (h) Lentiviral Particles - sc-95804-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU122401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2745 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2745 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00632 from Sigma-Aldrich
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ACRBP siRNA (Human) - CRJ3505 from Cohesion Biosciences
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ACRBP - MBS828701 from MyBioSource
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shRNA set against Human ACRBP (NM_032489.2) - SHH230646 from Creative biogene
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shRNA set against Human ACRBP(NM_032489.2) - SHG031229 from Creative biogene
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ACRBP shRNA Plasmid (Human) - CHJ3505 from Cohesion Biosciences
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ACRBP miRNA 3'UTR clone - MiUTR1H-00119 from Creative biogene
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