| Gene Symbol |
SLC16A2
|
| Entrez Gene |
6567
|
| Alt Symbol |
AHDS, DXS128, DXS128E, MCT 7, MCT 8, MCT7, MCT8, MRX22, XPCT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 16, member 2 (thyroid hormone transporter)
|
| Other Description |
X-linked PEST-containing transporter|monocarboxylate transporter 7|monocarboxylate transporter 8
|
| Swissprots |
P36021 Q7Z797
|
| Accessions |
AAB60375 EAW98644 EAW98645 P36021 AA205401 AB085789 BAC76827 AF055025 AK308542 AW022421 BC156062 AAI56063 BC156880 AAI56881 CN342861 U05315 AAB60374 XM_005262294 XP_005262351 XM_011531015 XP_011529317 NM_006517 NP_006508
|
| Function |
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in liver and heart.
|