Gene Symbol | SLC16A2 |
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Entrez Gene | 6567 |
Alt Symbol | AHDS, DXS128, DXS128E, MCT 7, MCT 8, MCT7, MCT8, MRX22, XPCT |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 16, member 2 (thyroid hormone transporter) |
Other Description | X-linked PEST-containing transporter|monocarboxylate transporter 7|monocarboxylate transporter 8 |
Swissprots | P36021 Q7Z797 |
Accessions | AAB60375 EAW98644 EAW98645 P36021 AA205401 AB085789 BAC76827 AF055025 AK308542 AW022421 BC156062 AAI56063 BC156880 AAI56881 CN342861 U05315 AAB60374 XM_005262294 XP_005262351 XM_011531015 XP_011529317 NM_006517 NP_006508 |
Function | Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Highly expressed in liver and heart. |
MCT8 CRISPR/Cas9 KO Plasmid (h) - sc-403824 from Santa Cruz Biotechnology
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MCT8 HDR Plasmid (h) - sc-403824-HDR from Santa Cruz Biotechnology
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MCT8 Double Nickase Plasmid (h) - sc-403824-NIC from Santa Cruz Biotechnology
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MCT8 Double Nickase Plasmid (h2) - sc-403824-NIC-2 from Santa Cruz Biotechnology
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MCT8 CRISPR Activation Plasmid (h) - sc-403824-ACT from Santa Cruz Biotechnology
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MCT8 CRISPR Activation Plasmid (h2) - sc-403824-ACT-2 from Santa Cruz Biotechnology
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MCT8 Lentiviral Activation Particles (h) - sc-403824-LAC from Santa Cruz Biotechnology
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MCT8 Lentiviral Activation Particles (h2) - sc-403824-LAC-2 from Santa Cruz Biotechnology
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MCT8 siRNA (h) - sc-61008 from Santa Cruz Biotechnology
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MCT8 shRNA Plasmid (h) - sc-61008-SH from Santa Cruz Biotechnology
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MCT8 shRNA (h) Lentiviral Particles - sc-61008-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU054001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2347 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2347 from Sigma-Aldrich
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SLC16A2 siRNA (Human) - CRH4456 from Cohesion Biosciences
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MCT8/SLC16A2 RNAi - H00006567-R01 from Novus Biologicals
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SLC16A2 - MBS8237165 from MyBioSource
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shRNA set against Human SLC16A2 (NM_006517.4) - SHH408624 from Creative biogene
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Human SLC16A2 siRNA - orb264958 from Biorbyt
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SLC16A2 shRNA Plasmid (Human) - CHH4456 from Cohesion Biosciences
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