Gene Symbol |
ERV3-1
|
Entrez Gene |
2086
|
Alt Symbol |
ERV-R, ERV3, ERVR, HERV-R, HERVR, envR
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
endogenous retrovirus group 3, member 1
|
Other Description |
ERV-3 envelope protein|ERV-R envelope protein|ERV3-1 envelope protein|HERV-R envelope protein|HERV-R_7q21.2 provirus ancestral Env polyprotein|endogenous retroviral sequence 3|endogenous retrovirus group 3 member 1 Env polyprotein
|
Swissprots |
Q14264
|
Accessions |
AAA88027 Q14264 AK074464 AK097499 AK295189 BAG58193 BC063605 DA198800 NM_001007253 NP_001007254
|
Function |
TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity). {ECO:0000250}.
|
Subcellular Location |
Virion.
|
Tissue Specificity |
Expressed at higher level in adrenal, sebaceous glands and placenta. Expressed at lower level in bone marrow, brain, breast, colon, heart, kidney, liver, lung, ovary, PBL, prostate, skin, spleen, testis, thymus, thyroid, trachea. {ECO:0000269|PubMed:12970426}.
|