Gene Symbol | ERV3-1 |
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Entrez Gene | 2086 |
Alt Symbol | ERV-R, ERV3, ERVR, HERV-R, HERVR, envR |
Species | Human |
Gene Type | protein-coding |
Description | endogenous retrovirus group 3, member 1 |
Other Description | ERV-3 envelope protein|ERV-R envelope protein|ERV3-1 envelope protein|HERV-R envelope protein|HERV-R_7q21.2 provirus ancestral Env polyprotein|endogenous retroviral sequence 3|endogenous retrovirus group 3 member 1 Env polyprotein |
Swissprots | Q14264 |
Accessions | AAA88027 Q14264 AK074464 AK097499 AK295189 BAG58193 BC063605 DA198800 NM_001007253 NP_001007254 |
Function | TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity). {ECO:0000250}. |
Subcellular Location | Virion. |
Tissue Specificity | Expressed at higher level in adrenal, sebaceous glands and placenta. Expressed at lower level in bone marrow, brain, breast, colon, heart, kidney, liver, lung, ovary, PBL, prostate, skin, spleen, testis, thymus, thyroid, trachea. {ECO:0000269|PubMed:12970426}. |
ERV3 CRISPR/Cas9 KO Plasmid (h) - sc-410773 from Santa Cruz Biotechnology
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ERV3 HDR Plasmid (h) - sc-410773-HDR from Santa Cruz Biotechnology
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ERV3 Double Nickase Plasmid (h) - sc-410773-NIC from Santa Cruz Biotechnology
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ERV3 Double Nickase Plasmid (h2) - sc-410773-NIC-2 from Santa Cruz Biotechnology
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ERV3 CRISPR Activation Plasmid (h) - sc-410773-ACT from Santa Cruz Biotechnology
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ERV3 CRISPR Activation Plasmid (h2) - sc-410773-ACT-2 from Santa Cruz Biotechnology
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ERV3 Lentiviral Activation Particles (h) - sc-410773-LAC from Santa Cruz Biotechnology
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ERV3 Lentiviral Activation Particles (h2) - sc-410773-LAC-2 from Santa Cruz Biotechnology
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ERV3 siRNA (h) - sc-89473 from Santa Cruz Biotechnology
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ERV3 shRNA Plasmid (h) - sc-89473-SH from Santa Cruz Biotechnology
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ERV3 shRNA (h) Lentiviral Particles - sc-89473-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7979 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7979 from Sigma-Aldrich
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ERV3-1 siRNA (Human) - CRH1454 from Cohesion Biosciences
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ERV3-1 - MBS8219044 from MyBioSource
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shRNA set against Human Erv3 (NM_001007253.3) - SHH287277 from Creative biogene
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ERV3-1 shRNA Plasmid (Human) - CHH1454 from Cohesion Biosciences
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ERV3-1 miRNA 3'UTR clone - MiUTR3H-00721 from Creative biogene
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