Gene Symbol |
Grin2a
|
Entrez Gene |
14811
|
Alt Symbol |
GluN2A, NMDAR2A, NR2A
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
|
Other Description |
GluRepsilon1|N-methyl D-aspartate receptor subtype 2A|glutamate [NMDA] receptor subunit epsilon-1|glutamate receptor ionotropic, NMDA 2A
|
Swissprots |
P35436
|
Accessions |
P35436 AK086290 AK149258 BC146289 AAI46290 BC148800 AAI48801 D10217 BAA01069 XM_006521794 XP_006521857 XM_006521795 XP_006521858 NM_008170 NP_032196
|
Function |
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
|
Subcellular Location |
Cell membrane {ECO:0000269|PubMed:14602821}; Multi-pass membrane protein {ECO:0000269|PubMed:14602821}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:14602821}; Multi-pass membrane protein {ECO:0000269|PubMed:14602821}.
|
Top Pathways |
Rap1 signaling pathway, Alcoholism, Cocaine addiction, Circadian entrainment, cAMP signaling pathway
|