Gene Symbol | AP3D1 |
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Entrez Gene | 8943 |
Alt Symbol | ADTD, hBLVR |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 3, delta 1 subunit |
Other Description | AP-3 complex delta subunit, partial CDS|AP-3 complex subunit delta|AP-3 complex subunit delta-1|adapter-related protein complex 3 subunit delta-1|adaptin, delta|adaptor-related protein complex 3 subunit delta-1|delta adaptin|delta-adaptin, partial CDS|subunit of putative vesicle coat adaptor complex AP-3 |
Swissprots | Q96G11 O00202 Q9H3C6 O75262 O14617 Q59HF5 |
Accessions | AAC25623 AAC27670 AAC34212 AAC34214 EAW69412 EAW69416 O14617 AB208804 BAD92041 AF002163 AAC51761 AF130042 AAG35473 AK094460 BAG52868 AK128692 AK310099 AK315899 BAF98790 AY954498 BC005142 AAH05142 BC010065 AAH10065 BC022837 BM982261 BQ227203 JF432332 ADZ15549 U91930 AAD03777 XM_006722932 XP_006722995 NM_001077523 NM_001261826 NP_001248755 NM_003938 NP_003929 |
Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
Subcellular Location | Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
Tissue Specificity | Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis. {ECO:0000269|PubMed:9151686}. |
Top Pathways | Lysosome |
AP-3δ (C-17) - sc-46768 from Santa Cruz Biotechnology
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AP-3δ (N-18) - sc-46772 from Santa Cruz Biotechnology
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AP-3δ1 (K-20) - sc-49154 from Santa Cruz Biotechnology
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AP-3δ1 (N-15) - sc-49155 from Santa Cruz Biotechnology
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AP-3δ (18) - sc-136277 from Santa Cruz Biotechnology
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Anti-AP3 antibody - ab85075 from Abcam
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Anti-AP3 antibody - ab90520 from Abcam
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Anti-AP3 antibody - ab3705 from Abcam
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Anti-AP3D1 / Adaptin Delta Antibody (Internal) - LS-C137156 from LifeSpan Bioscience
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Anti-AP3D1 / Adaptin Delta Antibody - LS-C136880 from LifeSpan Bioscience
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Anti-AP3D1 / Adaptin Delta Antibody (aa686-698) IHC-plus⢠- LS-B345 from LifeSpan Bioscience
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AP3D1 Antibody - NBP2-27158 from Novus Biologicals
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AP3D1 Antibody - NBP1-02453 from Novus Biologicals
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Anti-AP3D1 antibody produced in goat - SAB2900325 from Sigma-Aldrich
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Ap3D1 antibody - GTX23705 from GeneTex
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Anti -AP3D1 (AP-3 Complex Subunit delta-1, AP-3 Complex Subunit delta, Adapter-relatedProtein Complex 3 Subunit delta-1, Delta-adaptin, PRO0039) - A2298-61A from USBiological Life Science
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Anti -AP3D1 (D-adaptin 3, AP-3 complex delta subunit and D-adaptin) - 168027 from USBiological Life Science
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AP3D1 antibody - 70R-15752 from Fitzgerald
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AP3D1 Antibody (OALA03346) - OALA03346 from Aviva Systems Biology
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AP3D1 Antibody - abx038276 from Abbexa
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AP3 complex subunit delta-1 antibody - 16454-1-AP from Acris Antibodies
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AP3 complex subunit delta-1 / AP3D1 (686-698) antibody - AP07559PU-N from Acris Antibodies
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AP3 complex subunit delta-1 (686-698) antibody - AP09210PU-N from Acris Antibodies
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AP3 complex subunit delta-1 antibody - H00008943-B01P from Acris Antibodies
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AP3 complex subunit delta-1 antibody - PAB9965 from Acris Antibodies
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