| Gene Symbol |
AP3D1
|
| Entrez Gene |
8943
|
| Alt Symbol |
ADTD, hBLVR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adaptor-related protein complex 3, delta 1 subunit
|
| Other Description |
AP-3 complex delta subunit, partial CDS|AP-3 complex subunit delta|AP-3 complex subunit delta-1|adapter-related protein complex 3 subunit delta-1|adaptin, delta|adaptor-related protein complex 3 subunit delta-1|delta adaptin|delta-adaptin, partial CDS|subunit of putative vesicle coat adaptor complex AP-3
|
| Swissprots |
Q96G11 O00202 Q9H3C6 O75262 O14617 Q59HF5
|
| Accessions |
AAC25623 AAC27670 AAC34212 AAC34214 EAW69412 EAW69416 O14617 AB208804 BAD92041 AF002163 AAC51761 AF130042 AAG35473 AK094460 BAG52868 AK128692 AK310099 AK315899 BAF98790 AY954498 BC005142 AAH05142 BC010065 AAH10065 BC022837 BM982261 BQ227203 JF432332 ADZ15549 U91930 AAD03777 XM_006722932 XP_006722995 NM_001077523 NM_001261826 NP_001248755 NM_003938 NP_003929
|
| Function |
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
|
| Tissue Specificity |
Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis. {ECO:0000269|PubMed:9151686}.
|
| Top Pathways |
Lysosome
|