Gene Symbol | ITGA1 |
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Entrez Gene | 3672 |
Alt Symbol | CD49a, VLA1 |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha 1 |
Other Description | CD49 antigen-like family member A|VLA-1|integrin alpha-1|laminin and collagen receptor|very late activation protein 1 |
Swissprots | B2RNU0 P56199 |
Accessions | CCF77001 P56199 AK300423 BAG62150 BC050277 BC137121 AAI37122 BC137122 AAI37123 BX640981 BX648284 X68742 NM_181501 NP_852478 |
Function | Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. {ECO:0000269|PubMed:15592458}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
Integrin α1 (A-9) - sc-271034 from Santa Cruz Biotechnology
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Integrin α1 (F-19) - sc-6584 from Santa Cruz Biotechnology
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Integrin α1 (R-164) - sc-10728 from Santa Cruz Biotechnology
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Integrin α1 (R-19) - sc-6583 from Santa Cruz Biotechnology
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Integrin α1 (TS2/7.1.1) - sc-81733 from Santa Cruz Biotechnology
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Anti-Integrin alpha 1 antibody - ab106267 from Abcam
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Anti-Integrin alpha 1 antibody - ab90279 from Abcam
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Anti-Integrin alpha 1 antibody - ab200570 from Abcam
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Anti-Integrin alpha 1 antibody [TS2/7] - ab34445 from Abcam
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Anti-Integrin alpha 1 antibody [TS2/7] (Biotin) - ab34160 from Abcam
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Anti-Integrin alpha 1 antibody [TS2/7] (FITC) - ab34176 from Abcam
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Anti-Integrin alpha 1 antibody [TS2/7] (Phycoerythrin) - ab58428 from Abcam
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Anti-Integrin alpha 1 antibody - C-terminal - ab181434 from Abcam
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (aa1121-1134) - LS-C343859 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (aa29-1141, clone TS106) - LS-C191454 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (clone TS2/7) - LS-C202291 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (Internal, Biotin) - LS-C278398 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (Internal, AP) - LS-C278397 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (Internal, Azide-free, HRP) - LS-C278400 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (Internal, APC) - LS-C278399 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (Internal, FITC) - LS-C278401 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody - LS-C308546 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (Internal, PE) - LS-C278402 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (Internal) - LS-C330473 from LifeSpan Bioscience
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Anti-ITGA1/CD49a/Integrin Alpha 1 Antibody (C-Terminus) - LS-C171760 from LifeSpan Bioscience
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