ITGA1

Gene Symbol	ITGA1
Entrez Gene	3672
Alt Symbol	CD49a, VLA1
Species	Human
Gene Type	protein-coding
Description	integrin, alpha 1
Other Description	CD49 antigen-like family member A|VLA-1|integrin alpha-1|laminin and collagen receptor|very late activation protein 1
Swissprots	B2RNU0 P56199
Accessions	CCF77001 P56199 AK300423 BAG62150 BC050277 BC137121 AAI37122 BC137122 AAI37123 BX640981 BX648284 X68742 NM_181501 NP_852478
Function	Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. {ECO:0000269|PubMed:15592458}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Integrin α1 CRISPR/Cas9 KO Plasmid (h) - sc-401275 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 HDR Plasmid (h) - sc-401275-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 Double Nickase Plasmid (h) - sc-401275-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 Double Nickase Plasmid (h2) - sc-401275-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 CRISPR Activation Plasmid (h) - sc-401275-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 CRISPR Activation Plasmid (h2) - sc-401275-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 Lentiviral Activation Particles (h) - sc-401275-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 Lentiviral Activation Particles (h2) - sc-401275-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 siRNA (h) - sc-43125 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Integrin α1 shRNA Plasmid (h) - sc-43125-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Integrin α1 shRNA (h) Lentiviral Particles - sc-43125-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU226461 from Sigma-Aldrich Category siRNA Prices $140.00, $140.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1532 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1532 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08530 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08530

ITGA1 siRNA (Human) - CRH2463 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Integrin alpha 1/CD49a RNAi - H00003672-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ITGA1 - MBS8238498 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Integrin α1 CRISPR/Cas9 KO Plasmid (h2) - sc-401275-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α1 HDR Plasmid (h2) - sc-401275-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human ITGA1 (NM_181501.1) - SHH321125 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ITGA1(NM_181501.1) - SHL175138 from Creative biogene Category siRNA Species Reactivities Human

Human ITGA1 siRNA - orb262965 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ITGA1 shRNA Plasmid (Human) - CHH2463 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ITGA1 miRNA 3'UTR clone - MiUTR1H-05016 from Creative biogene Species Reactivities Human

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