Gene Symbol |
ATG101
|
Entrez Gene |
60673
|
Alt Symbol |
C12orf44
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
autophagy related 101
|
Other Description |
Atg13-interacting protein|autophagy-related protein 101
|
Swissprots |
Q9BSB4 Q9HBN1 Q9HAE2
|
Accessions |
EAW58229 EAW58230 Q9BSB4 AF218031 AAG17273 AK021835 BAB13907 BC005151 AAH05151 BC009937 AAH09937 BC064533 BP309508 CB137838 NM_001098673 NP_001092143 NM_021934 NP_068753
|
Function |
Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation. {ECO:0000269|PubMed:19287211, ECO:0000269|PubMed:19597335}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19597335}. Preautophagosomal structure {ECO:0000269|PubMed:19597335}. Note=Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
|