Gene Symbol | ATG101 |
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Entrez Gene | 60673 |
Alt Symbol | C12orf44 |
Species | Human |
Gene Type | protein-coding |
Description | autophagy related 101 |
Other Description | Atg13-interacting protein|autophagy-related protein 101 |
Swissprots | Q9BSB4 Q9HBN1 Q9HAE2 |
Accessions | EAW58229 EAW58230 Q9BSB4 AF218031 AAG17273 AK021835 BAB13907 BC005151 AAH05151 BC009937 AAH09937 BC064533 BP309508 CB137838 NM_001098673 NP_001092143 NM_021934 NP_068753 |
Function | Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation. {ECO:0000269|PubMed:19287211, ECO:0000269|PubMed:19597335}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19597335}. Preautophagosomal structure {ECO:0000269|PubMed:19597335}. Note=Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. |
C12orf44 CRISPR/Cas9 KO Plasmid (h) - sc-412948 from Santa Cruz Biotechnology
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C12orf44 HDR Plasmid (h) - sc-412948-HDR from Santa Cruz Biotechnology
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C12orf44 Double Nickase Plasmid (h) - sc-412948-NIC from Santa Cruz Biotechnology
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C12orf44 Double Nickase Plasmid (h2) - sc-412948-NIC-2 from Santa Cruz Biotechnology
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C12orf44 CRISPR Activation Plasmid (h) - sc-412948-ACT from Santa Cruz Biotechnology
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C12orf44 CRISPR Activation Plasmid (h2) - sc-412948-ACT-2 from Santa Cruz Biotechnology
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C12orf44 Lentiviral Activation Particles (h) - sc-412948-LAC from Santa Cruz Biotechnology
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C12orf44 Lentiviral Activation Particles (h2) - sc-412948-LAC-2 from Santa Cruz Biotechnology
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C12orf44 siRNA (h) - sc-95858 from Santa Cruz Biotechnology
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C12orf44 shRNA Plasmid (h) - sc-95858-SH from Santa Cruz Biotechnology
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C12orf44 shRNA (h) Lentiviral Particles - sc-95858-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU086061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4255 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4255 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01749 from Sigma-Aldrich
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ATG101 siRNA (Human) - CRJ1824 from Cohesion Biosciences
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ATG101 - MBS8225465 from MyBioSource
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shRNA set against Human C12orf44 (NM_021934.4) - SHH249106 from Creative biogene
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Human ATG101 siRNA - orb272325 from Biorbyt
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ATG101 shRNA Plasmid (Human) - CHJ1824 from Cohesion Biosciences
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C12ORF44 miRNA 3'UTR clone - MiUTR1H-01064 from Creative biogene
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C12ORF44 miRNA 3'UTR clone - MiUTR3H-13730 from Creative biogene
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