| Gene Symbol |
TCF23
|
| Entrez Gene |
150921
|
| Alt Symbol |
OUT, TCF-23, bHLHa24
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription factor 23
|
| Other Description |
class A basic helix-loop-helix protein 24|class II basic helix-loop-helix protein TCF23
|
| Swissprots |
Q7RTU1 B2RNZ3
|
| Accessions |
DAA00305 EAX00624 Q7RTU1 BC137191 AAI37192 BC137192 AAI37193 BC144525 XM_005264159 XP_005264216 NM_175769 NP_786951
|
| Function |
Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
|
| Tissue Specificity |
Expressed in liver, kidney and spleen. {ECO:0000269|PubMed:14516699}.
|