Gene Symbol | TCF23 |
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Entrez Gene | 150921 |
Alt Symbol | OUT, TCF-23, bHLHa24 |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor 23 |
Other Description | class A basic helix-loop-helix protein 24|class II basic helix-loop-helix protein TCF23 |
Swissprots | Q7RTU1 B2RNZ3 |
Accessions | DAA00305 EAX00624 Q7RTU1 BC137191 AAI37192 BC137192 AAI37193 BC144525 XM_005264159 XP_005264216 NM_175769 NP_786951 |
Function | Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. |
Tissue Specificity | Expressed in liver, kidney and spleen. {ECO:0000269|PubMed:14516699}. |
TCF23 CRISPR/Cas9 KO Plasmid (h) - sc-414692 from Santa Cruz Biotechnology
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TCF23 HDR Plasmid (h) - sc-414692-HDR from Santa Cruz Biotechnology
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TCF23 Double Nickase Plasmid (h) - sc-414692-NIC from Santa Cruz Biotechnology
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TCF23 Double Nickase Plasmid (h2) - sc-414692-NIC-2 from Santa Cruz Biotechnology
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TCF23 CRISPR Activation Plasmid (h) - sc-414692-ACT from Santa Cruz Biotechnology
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TCF23 CRISPR Activation Plasmid (h2) - sc-414692-ACT-2 from Santa Cruz Biotechnology
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TCF23 Lentiviral Activation Particles (h) - sc-414692-LAC from Santa Cruz Biotechnology
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TCF23 Lentiviral Activation Particles (h2) - sc-414692-LAC-2 from Santa Cruz Biotechnology
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TCF23 siRNA (h) - sc-94492 from Santa Cruz Biotechnology
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TCF23 shRNA Plasmid (h) - sc-94492-SH from Santa Cruz Biotechnology
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TCF23 shRNA (h) Lentiviral Particles - sc-94492-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN21143 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21143 from Sigma-Aldrich
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TCF23 siRNA (Human) - CRJ5677 from Cohesion Biosciences
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TCF23 - MBS8232668 from MyBioSource
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shRNA set against Human Tcf23 (NM_175769.2) - SHH424800 from Creative biogene
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Human TCF23 siRNA - orb276178 from Biorbyt
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TCF23 shRNA Plasmid (Human) - CHJ5677 from Cohesion Biosciences
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TCF23 miRNA 3'UTR clone - MiUTR4H-TG08853 from Creative biogene
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