Gene Symbol | BTNL8 |
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Entrez Gene | 79908 |
Alt Symbol | BTN9.2 |
Species | Human |
Gene Type | protein-coding |
Description | butyrophilin-like 8 |
Other Description | B7-H5 costimulatory molecule|butyrophilin-like protein 8 |
Swissprots | E9PEF6 A4QMZ8 B7Z5B1 A6NEX6 F2Z2B2 F8W712 B7Z409 Q9H730 Q6UX41 E9PG07 |
Accessions | EAW53732 EAW53733 Q6UX41 AK025111 BAB15069 AK225213 AK296597 BAH12395 AK298687 BAH12847 AK308012 AK309639 AY358523 AAQ88887 BC119696 AAI19697 BC119697 DA425770 XM_011534649 XP_011532951 XM_011534650 XP_011532952 XM_011534651 XP_011532953 XM_011534652 XP_011532954 XM_011534653 XP_011532955 NM_001040462 NP_001035552 NM_001159707 NP_001153179 NM_001159708 NP_001153180 NM_001159709 NP_001153181 NM_001159710 NP_001153182 NM_024850 NP_079126 |
Function | May stimulate primary immune response. Acts on T-cell stimulated sub-optimally through the TCR/CD3 complex stimulating their proliferation and cytokine production. {ECO:0000269|PubMed:24036152}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in neutrophils. Isoforms 1 and 5 are expressed at high levels in the colon, lung,testis, lymph nodes and thyroid tissue. Isoform 5, but not isoform 1, is detected in spleen. {ECO:0000269|PubMed:24036152}. |
BTNL8 CRISPR/Cas9 KO Plasmid (h) - sc-406482 from Santa Cruz Biotechnology
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BTNL8 HDR Plasmid (h) - sc-406482-HDR from Santa Cruz Biotechnology
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BTNL8 Double Nickase Plasmid (h) - sc-406482-NIC from Santa Cruz Biotechnology
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BTNL8 Double Nickase Plasmid (h2) - sc-406482-NIC-2 from Santa Cruz Biotechnology
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BTNL8 CRISPR Activation Plasmid (h) - sc-406482-ACT from Santa Cruz Biotechnology
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BTNL8 CRISPR Activation Plasmid (h2) - sc-406482-ACT-2 from Santa Cruz Biotechnology
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BTNL8 Lentiviral Activation Particles (h) - sc-406482-LAC from Santa Cruz Biotechnology
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BTNL8 Lentiviral Activation Particles (h2) - sc-406482-LAC-2 from Santa Cruz Biotechnology
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BTNL8 siRNA (h) - sc-91741 from Santa Cruz Biotechnology
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BTNL8 shRNA Plasmid (h) - sc-91741-SH from Santa Cruz Biotechnology
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BTNL8 shRNA (h) Lentiviral Particles - sc-91741-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU126931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4117 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4117 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07335 from Sigma-Aldrich
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BTNL8 siRNA (Human) - CRJ2659 from Cohesion Biosciences
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BTNL8 - MBS8234503 from MyBioSource
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shRNA set against Human BTNL8 (NM_024850.2) - SHH248406 from Creative biogene
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BTNL8 shRNA Plasmid (Human) - CHJ2659 from Cohesion Biosciences
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BTNL8 miRNA 3'UTR clone - MiUTR4H-TG00873 from Creative biogene
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