| Gene Symbol |
AP5S1
|
| Entrez Gene |
55317
|
| Alt Symbol |
C20orf29
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adaptor-related protein complex 5, sigma 1 subunit
|
| Other Description |
AP-5 complex subunit sigma-1|adapter-related protein complex 5 sigma subunit|adaptor-related protein complex 5 sigma subunit|protein C20orf29|sigma5
|
| Swissprots |
B3KSD0 Q9NUS5 D3DVY7
|
| Accessions |
CAE89984 CAK32303 EAX10483 EAX10484 EAX10485 EAX10486 Q9NUS5 AI338486 AK002030 BAA92045 AK093332 BAG52692 BC011985 BC043344 AAH43344 DA129391 DA253969 DB190907 NM_001204446 NP_001191375 NM_001204447 NP_001191376 NM_018347 NP_060817
|
| Function |
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862, it is required for efficient homologous recombination DNA double-strand break repair. {ECO:0000269|PubMed:20613862, ECO:0000269|PubMed:22022230}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:22022230}. Late endosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Lysosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}.
|
![Western Blot: C20orf29 Overexpression Lysate (Adult Normal) [NBL1-08370] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C20orf29.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11227_C20orf29%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-08370-img0002.jpg)