Gene Symbol | AP5S1 |
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Entrez Gene | 55317 |
Alt Symbol | C20orf29 |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 5, sigma 1 subunit |
Other Description | AP-5 complex subunit sigma-1|adapter-related protein complex 5 sigma subunit|adaptor-related protein complex 5 sigma subunit|protein C20orf29|sigma5 |
Swissprots | B3KSD0 Q9NUS5 D3DVY7 |
Accessions | CAE89984 CAK32303 EAX10483 EAX10484 EAX10485 EAX10486 Q9NUS5 AI338486 AK002030 BAA92045 AK093332 BAG52692 BC011985 BC043344 AAH43344 DA129391 DA253969 DB190907 NM_001204446 NP_001191375 NM_001204447 NP_001191376 NM_018347 NP_060817 |
Function | As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862, it is required for efficient homologous recombination DNA double-strand break repair. {ECO:0000269|PubMed:20613862, ECO:0000269|PubMed:22022230}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:22022230}. Late endosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Lysosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. |
C20orf29 CRISPR/Cas9 KO Plasmid (h) - sc-417069 from Santa Cruz Biotechnology
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C20orf29 HDR Plasmid (h) - sc-417069-HDR from Santa Cruz Biotechnology
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C20orf29 Double Nickase Plasmid (h) - sc-417069-NIC from Santa Cruz Biotechnology
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C20orf29 Double Nickase Plasmid (h2) - sc-417069-NIC-2 from Santa Cruz Biotechnology
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C20orf29 CRISPR Activation Plasmid (h) - sc-417069-ACT from Santa Cruz Biotechnology
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C20orf29 CRISPR Activation Plasmid (h2) - sc-417069-ACT-2 from Santa Cruz Biotechnology
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C20orf29 Lentiviral Activation Particles (h) - sc-417069-LAC from Santa Cruz Biotechnology
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C20orf29 Lentiviral Activation Particles (h2) - sc-417069-LAC-2 from Santa Cruz Biotechnology
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C20orf29 siRNA (h) - sc-72730 from Santa Cruz Biotechnology
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C20orf29 shRNA Plasmid (h) - sc-72730-SH from Santa Cruz Biotechnology
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C20orf29 shRNA (h) Lentiviral Particles - sc-72730-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU026331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4742 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4742 from Sigma-Aldrich
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AP5S1 siRNA (Human) - CRJ0650 from Cohesion Biosciences
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AP5S1 - MBS8216338 from MyBioSource
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shRNA set against Human C20orf29 (NM_018347.2) - SHH251061 from Creative biogene
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Human AP5S1 siRNA - orb271151 from Biorbyt
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AP5S1 shRNA Plasmid (Human) - CHJ0650 from Cohesion Biosciences
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AP5S1 miRNA 3'UTR clone - MiUTR4H-TG01499 from Creative biogene
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