| Gene Symbol |
SSTR1
|
| Entrez Gene |
6751
|
| Alt Symbol |
SRIF-2, SS-1-R, SS1-R, SS1R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
somatostatin receptor 1
|
| Other Description |
somatostatin receptor type 1
|
| Swissprots |
P30872
|
| Accessions |
AAA58247 AAP84349 CBE74677 CDM63479 EAW65836 P30872 AK290868 BAF83557 BC035618 AAH35618 BX248780 CAD66587 DQ893328 ABM84254 DQ896644 ABM87643 NM_001049 NP_001040
|
| Function |
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
|
| Top Pathways |
cAMP signaling pathway, Neuroactive ligand-receptor interaction
|
![Western Blot: Somatostatin Receptor 1 Overexpression Lysate (Adult Normal) [NBL1-16477] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Somatostatin Receptor 1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9141_Somatostatin%2520Receptor%25201%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16477-img0002.jpg)