Gene Symbol | SSTR1 |
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Entrez Gene | 6751 |
Alt Symbol | SRIF-2, SS-1-R, SS1-R, SS1R |
Species | Human |
Gene Type | protein-coding |
Description | somatostatin receptor 1 |
Other Description | somatostatin receptor type 1 |
Swissprots | P30872 |
Accessions | AAA58247 AAP84349 CBE74677 CDM63479 EAW65836 P30872 AK290868 BAF83557 BC035618 AAH35618 BX248780 CAD66587 DQ893328 ABM84254 DQ896644 ABM87643 NM_001049 NP_001040 |
Function | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach. |
Top Pathways | cAMP signaling pathway, Neuroactive ligand-receptor interaction |
SSTR1 CRISPR/Cas9 KO Plasmid (h) - sc-403410 from Santa Cruz Biotechnology
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SSTR1 HDR Plasmid (h) - sc-403410-HDR from Santa Cruz Biotechnology
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SSTR1 Double Nickase Plasmid (h) - sc-403410-NIC from Santa Cruz Biotechnology
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SSTR1 Double Nickase Plasmid (h2) - sc-403410-NIC-2 from Santa Cruz Biotechnology
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SSTR1 CRISPR Activation Plasmid (h) - sc-403410-ACT from Santa Cruz Biotechnology
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SSTR1 CRISPR Activation Plasmid (h2) - sc-403410-ACT-2 from Santa Cruz Biotechnology
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SSTR1 Lentiviral Activation Particles (h) - sc-403410-LAC from Santa Cruz Biotechnology
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SSTR1 Lentiviral Activation Particles (h2) - sc-403410-LAC-2 from Santa Cruz Biotechnology
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SSTR1 siRNA (h) - sc-42267 from Santa Cruz Biotechnology
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SSTR1 shRNA Plasmid (h) - sc-42267-SH from Santa Cruz Biotechnology
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SSTR1 shRNA (h) Lentiviral Particles - sc-42267-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU025621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20634 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20634 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11566 from Sigma-Aldrich
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SSTR1 siRNA (Human) - CRH4614 from Cohesion Biosciences
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Somatostatin R1/SSTR1 RNAi - H00006751-R02 from Novus Biologicals
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SSTR1 - MBS8221483 from MyBioSource
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shRNA set against Human SSTR1 (NM_001049.2) - SHH418568 from Creative biogene
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shRNA set against Human SSTR1(NM_001049.2) - SHL036864 from Creative biogene
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SSTR1 shRNA Plasmid (Human) - CHH4614 from Cohesion Biosciences
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SSTR1 miRNA 3'UTR clone - MiUTR1H-09930 from Creative biogene
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