| Gene Symbol |
CAPN8
|
| Entrez Gene |
388743
|
| Alt Symbol |
nCL-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calpain 8
|
| Other Description |
calpain-8|new calpain 2|stomach-specific M-type calpain
|
| Swissprots |
A6NHC0 B2RXL2
|
| Accessions |
A6NHC0 BC157893 AAI57894 BG187068 BM739137 BM843240 DA874912 NM_001143962 NP_001137434
|
| Function |
Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}.
|
| Tissue Specificity |
Stomach.
|